ResultsOf 76 eligible practices contacted, 12 accepted, and eight were selected, randomised and participated for the duration of the trial. Blinding post-randomisation was not possible but outcome measurement and analysis were masked. Recruitment and baseline measurements occurred prior to randomisation. Cost-effectiveness from a health service perspective, engagement, and retention were assessed. Primary outcomes were quality of life (EQ-5D-5L utility scores) and well-being (W-BQ12 3 domains). Control practices continued treatment as usual. The intervention comprised structured longer consultations, relationship continuity, practitioner support, and self-management support.
HOMEM ALPHA PDF TRIAL
We used a phase 2 exploratory cluster randomised controlled trial with eight general practices in Glasgow in very deprived areas that involved multimorbid patients aged 30–65 years. Our aim was to evaluate a whole-system primary care-based complex intervention, called CARE Plus, to improve quality of life in multimorbid patients living in areas of very high deprivation. Multimorbidity is common in deprived communities and reduces quality of life. While mindfulness meditation improves pain and depression symptoms and quality of life, additional well-designed, rigorous, and large-scale RCTs are needed to decisively provide estimates of the efficacy of mindfulness meditation for chronic pain. Statistically significant effects were also found for depression symptoms and quality of life. We found low-quality evidence that mindfulness meditation is associated with a small decrease in pain compared with all types of controls in 30 RCTs. ResultsThirty-eight RCTs met inclusion criteria seven reported on safety. Outcomes included pain, depression, quality of life, and analgesic use. Quality of evidence was assessed using the GRADE approach. We conducted a systematic review on randomized controlled trials (RCTs) with meta-analyses using the Hartung-Knapp-Sidik-Jonkman method for random-effects models. PurposeThis study aims to synthesize evidence on efficacy and safety of mindfulness meditation interventions for the treatment of chronic pain in adults.
Chronic pain patients increasingly seek treatment through mindfulness meditation.
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